Ezatiostat

Ezatiostat (TER199 free base; TLK199) is a tripeptide analog of glutathione and is a selective and orally active glutathione S-transferase P1-1 (GSTP1) inhibitor. Ezatiostat leads to JNK activation by inhibiting GSTP1. Ezatiostat stimulates both lymphocyte production and bone marrow progenitor proliferation. Ezatiostat has the potential for myelodysplastic syndrome (MDS) treatment.

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CAT#	HB00099
Chemical Structure
CAS	168682-53-9
Background	Ezatiostat (TER199 free base; TLK199) is a tripeptide analog of glutathione and is a selective and orally active glutathione S-transferase P1-1 (GSTP1) inhibitor. Ezatiostat leads to JNK activation by inhibiting GSTP1. Ezatiostat stimulates both lymphocyte production and bone marrow progenitor proliferation. Ezatiostat has the potential for myelodysplastic syndrome (MDS) treatment.
Synonyms/Alias	TER199(free base); TLK199
M.F/Formula	C27H35N3O6S
M.W/Mr.	529.65
Activity	Inhibitor
Target	Gutathione S-transferase

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Storage	Desiccate at -20°C
Shipping Condition	Room temperature in continental US; may vary elsewhere.