Endomorphin 2

Endomorphin-2 is a peptide amide with the highest known affinity and specificity for the mu-opioid receptor.

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CAT#R1853
CAS141801-26-5
Chemical Name(2S)-1-[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]-N-[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]pyrrolidine-2-carboxamide
M.F/FormulaC32H37N5O5
M.W/Mr.571.7
SequenceOne Letter Code: YPFF (Modifications: Phe-3 = C-terminal amide)
Three Letter Code: H-Tyr-Pro-Phe-Phe-NH2
Purity> 95%
ActivityEndogenous peptide with extremely high affinity and selectivity for μ-opioid receptors (with Ki values of 0.69, 9233 and 5240 nM for μ, δ and κ respectively).
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