Endomorphin-2 is a peptide amide with the highest known affinity and specificity for the mu-opioid receptor.
CAT# | R1853 |
CAS | 141801-26-5 |
Chemical Name | (2S)-1-[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]-N-[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]pyrrolidine-2-carboxamide |
M.F/Formula | C32H37N5O5 |
M.W/Mr. | 571.7 |
Sequence | One Letter Code: YPFF (Modifications: Phe-3 = C-terminal amide) Three Letter Code: H-Tyr-Pro-Phe-Phe-NH2 |
Purity | > 95% |
Activity | Endogenous peptide with extremely high affinity and selectivity for μ-opioid receptors (with Ki values of 0.69, 9233 and 5240 nM for μ, δ and κ respectively). |
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