Endomorphin 2

Endomorphin-2 is a peptide amide with the highest known affinity and specificity for the mu-opioid receptor.

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CAT#	R1853
CAS	141801-26-5
Chemical Name	(2S)-1-[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]-N-[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]pyrrolidine-2-carboxamide
M.F/Formula	C32H37N5O5
M.W/Mr.	571.7
Sequence	One Letter Code: YPFF (Modifications: Phe-3 = C-terminal amide) Three Letter Code: H-Tyr-Pro-Phe-Phe-NH2
Purity	> 95%
Activity	Endogenous peptide with extremely high affinity and selectivity for μ-opioid receptors (with Ki values of 0.69, 9233 and 5240 nM for μ, δ and κ respectively).

CAT#	Product Name	Inquiry
R1499	Magainin 1	Inquiry
R1678	SLLK, Control Peptide for TSP1 Inhibitor	Inquiry
R1438	H-Val-Pro-Pro-OH TFA	Inquiry
R1081	(d(CH2)51,Tyr(Me)2,Arg8)-Vasopressin	Inquiry
PI-001	GIP (1-39)	Inquiry

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Solubility	Soluble to 0.40 mg/ml in water
Shipping Condition	Evaluation sample solution : ship with blue ice; All other available size: ship with RT , or blue ice upon request
InChI	InChI=1S/C32H37N5O5/c33-25(18-23-13-15-24(38)16-14-23)32(42)37-17-7-12-28(37)31(41)36-27(20-22-10-5-2-6-11-22)30(40)35-26(29(34)39)19-21-8-3-1-4-9-21/h1-6,8-11,13-16,25-28,38H,7,12,17-20,33H2,(H2,34,39)(H,35,40)(H,36,41)/t25-,26-,27-,28-/m0/s1
InChI Key	XIJHWXXXIMEHKW-LJWNLINESA-N
Canonical SMILES	C1CC(N(C1)C(=O)C(CC2=CC=C(C=C2)O)N)C(=O)NC(CC3=CC=CC=C3)C(=O)NC(CC4=CC=CC=C4)C(=O)N
Isomeric SMILES	C1C[C@H](N(C1)C(=O)[C@H](CC2=CC=C(C=C2)O)N)C(=O)N[C@@H](CC3=CC=CC=C3)C(=O)N[C@@H](CC4=CC=CC=C4)C(=O)N