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Elamipretide TFA (MTP-131 TFA; RX-31 TFA; SS-31 TFA) is a cardiolipin peroxidase inhibitor and mitochondria-targeting peptide.
CAT No: R1338
CAS No: 1606994-55-1
Synonyms/Alias: Elamipretide (TFA);1606994-55-1;L-Phenylalaninamide, D-arginyl-2,6-dimethyl-L-tyrosyl-L-lysyl-, 2,2,2-trifluoroacetate (1:1);(S)-6-Amino-N-((S)-1-amino-1-oxo-3-phenylpropan-2-yl)-2-((S)-2-((R)-2-amino-5-guanidinopentanamido)-3-(4-hydroxy-2,6-dimethylphenyl)propanamido)hexanamide 2,2,2-trifluoroacetate;(2S)-6-amino-2-[[(2S)-2-[[(2R)-2-amino-5-(diaminomethylideneamino)pentanoyl]amino]-3-(4-hydroxy-2,6-dimethylphenyl)propanoyl]amino]-N-[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]hexanamide;2,2,2-trifluoroacetic acid;HY-P0125A;RX-31 (TFA);CS-0058610;G79489;
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M.F/Formula | C34H50F3N9O7 |
M.W/Mr. | 753.8 |
Sequence | One Letter Code:RXKF Three Letter Code:H-D-Arg-Tyr(2,6-diMe)-Lys-Phe-NH2.TFA |
InChI | InChI=1S/C32H49N9O5.C2HF3O2/c1-19-15-22(42)16-20(2)23(19)18-27(41-29(44)24(34)11-8-14-38-32(36)37)31(46)39-25(12-6-7-13-33)30(45)40-26(28(35)43)17-21-9-4-3-5-10-21;3-2(4,5)1(6)7/h3-5,9-10,15-16,24-27,42H,6-8,11-14,17-18,33-34H2,1-2H3,(H2,35,43)(H,39,46)(H,40,45)(H,41,44)(H4,36,37,38);(H,6,7)/t24-,25+,26+,27+;/m1./s1 |
InChI Key | WLZHRKGRZBGUJU-NFWUDPOKSA-N |
3. High fat diet and GLP-1 drugs induce pancreatic injury in mice
4. Adipose tissue is a key organ for the beneficial effects of GLP-2 metabolic function
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