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Dynorphin A (1-10) (TFA), an endogenous opioid neuropeptide, binds to extracellular loop 2 of the κ-opioid receptor. Dynorphin A (1-10) (TFA) also blocks NMDA-activated current with an IC50 of 42.0 μM.
Peptide Library Construction and Screening
Powerful screening tools in biological and chemical research
M.F/Formula | C₅₉H₉₂F₃N₁₉O₁₄ |
M.W/Mr. | 1348.48 |
Sequence | One Letter Code: YGGFLRRIRP three Letter Code: Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Ile-Arg-Pro |
1. Adipose tissue is a key organ for the beneficial effects of GLP-2 metabolic function
3. The spatiotemporal control of signalling and trafficking of the GLP-1R
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