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β-Casomorphin (1-2)

The antihypertensive peptide isolated from fermented milk had a low inhibitory activity against angiotensin I-converting enzyme (ACE), IC50 720 μM. The dipeptide is a possible biosynthetic precursor of endomorphin.

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CAT No: C10001

CAS No: 51871-47-7

Synonyms/Alias: beta-Casomorphin (1-2); b-Casomorphin (1-2); L-Tyrosyl-L-proline

Chemical Name: (2S)-1-[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]pyrrolidine-2-carboxylic acid

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M.F/FormulaC14H18N2O4
M.W/Mr.278.31
SequenceOne Letter Code: YP
Three Letter Code: H-Tyr-Pro-OH
AppearanceWhite or off-white lyophilized powder
ActivityInhibitor
Biological ActivityTyr-Pro is a dipeptide obtained by formal condensation of the carboxy group of L-tyrosine with the amino group of L-proline. It derives from a L-tyrosine and a L-proline.
Long-term Storage ConditionsSoluble in DMSO
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
InChIInChI=1S/C14H18N2O4/c15-11(8-9-3-5-10(17)6-4-9)13(18)16-7-1-2-12(16)14(19)20/h3-6,11-12,17H,1-2,7-8,15H2,(H,19,20)/t11-,12-/m0/s1
InChI KeyVNYDHJARLHNEGA-RYUDHWBXSA-N
Canonical SMILESC1CC(N(C1)C(=O)C(CC2=CC=C(C=C2)O)N)C(=O)O
Isomeric SMILESC1C[C@H](N(C1)C(=O)[C@H](CC2=CC=C(C=C2)O)N)C(=O)O
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