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Peptide Library Construction and Screening
Powerful screening tools in biological and chemical research
Sequence | AEAMSQVTNSTTIM |
Functions | Matrix protein p17 targets Gag and Gag-pol polyproteins to the plasma membrane via a multipartite membrane binding signal, that includes its myristoylated N-terminus. Also mediates nuclear localization of the preintegration complex. Implicated in the release from host cell mediated by Vpu. Capsid protein p24 forms the conical core of the virus that encapsulates the genomic RNA-nucleocapsid complex. Nucleocapsid protein p7 encapsulates and protects viral dimeric unspliced (genomic) RNA. Binds these RNAs through its zinc fingers (By similarity). The aspartyl protease mediates proteolytic cleavages of Gag and Gag-Pol polyproteins during or shortly after the release of the virion from the plasma membrane. Cleavages take place as an ordered, step-wise cascade to yield mature proteins. This process is called maturation. Displays maximal activity during the budding process just prior to particle release from the cell. Also cleaves Nef and Vif, probably concomitantly with viral structural proteins on maturation of virus particles (By similarity). |
Source# | Synthetic |
Solubility | -20°C |
2. TMEM16F and dynamins control expansive plasma membrane reservoirs
3. Implications of ligand-receptor binding kinetics on GLP-1R signalling
5. Autoinhibition and phosphorylation-induced activation of phospholipase C-γ isozymes
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