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This 7-amino-4-methylcoumarin (AMC) labeled peptide is widely used as a fluorogenic substrate for 20S proteasome, calpains and other chymotrypsin-like proteases. Cleavage of this AMC peptide by the enzymes generates strongly fluorescent AMC that is monitored fluorimetrically at Abs/Em=353/442 nm.
Peptide Library Construction and Screening
Powerful screening tools in biological and chemical research
M.W/Mr. | 763.9 |
Sequence | One Letter Code: Suc-LLVY-AMC Three Letter Code: Suc-Leu-Leu-Val-Tyr-AMC |
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