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PM_15814646

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SequenceGNQWFI
Functionspeptide inhibits binding of VEGF, placental growth factor (PlGF), and VEGF/PlGF heterodimer to VEGFR1; peptide blocks VEGF-induced migration of endothelial cells and their capacity to form capillary-like structures on fibrin gel-based in vitro angiogenesis system; peptide inhibits growth and metastasis of VEGF-secreting tumor cells in vivo when injected s. c. in nude mice
Source#Synthetic
Solubility-20°C
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