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Nonapeptide-1

Nonapeptide-1 can prevent melanin synthesis and unwanted pigmentation by preventing activation of the tyrosinase, thus allowing for a better control over skin tone.

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CAT No: CPC1650

CAS No: 158563-45-2

Synonyms/Alias: Nonapeptide-1;158563-45-2;H-Met-Pro-D-Phe-Arg-D-Trp-Phe-Lys-Pro-Val-NH2;White 05;Melanostatine 5;Nonapeptide-1 [INCI];(Met5,pro6,d-phe7,d-trp9,phe10)-alpha-msh (5-13);L-Valinamide, L-methionyl-L-prolyl-D-phenylalanyl-L-arginyl-D-tryptophyl-L-phenylalanyl-L-lysyl-L-prolyl-;UNII-64W45420K5;Met-pro-phe-arg-trp-phe-lys-pro-val;64W45420K5;Nonapeptide-1 (acetate);MFCD00672435;(S)-1-(L-methionyl)-N-((R)-1-(((S)-1-(((R)-1-(((S)-1-(((S)-6-amino-1-((S)-2-(((S)-1-amino-3-methyl-1-oxobutan-2-yl)carbamoyl)pyrrolidin-1-yl)-1-oxohexan-2-yl)amino)-1-oxo-3-phenylpropan-2-yl)amino)-3-(1H-indol-3-yl)-1-oxopropan-2-yl)amino)-5-guanidino-1-oxopentan-2-yl)amino)-1-oxo-3-phenylpropan-2-yl)pyrrolidine-2-carboxamide;Met-Pro-D-Phe-Arg-D-Trp-Phe-Lys-Pro-Val-NH2;(Met5,Pro6,D-Phe7,D-Trp9,Phe10)-a-MSH (5-13);KNFLNGRLKALWRF-LDXSYGEZSA-N;HY-P0097;AKOS030632860;AC-31945;DA-69171;DS-19607;FM108756;CS-0017927;C72990;Q27263795;(Met5,Pro6,D-Phe7,D-Trp9,Phe10)-?-MSH (5-13);Met-Pro-D-Phe-Arg-D-Trp-Phe-Lys-Pro-Val-NH2;Nonapeptide 1;(2S)-N-[(1R)-1-{[(1S)-1-{[(2S)-6-amino-1-[(2S)-2-{[(1S)-1-carbamoyl-2-methylpropyl]carbamoyl}pyrrolidin-1-yl]-1-oxohexan-2-yl]carbamoyl}-2-phenylethyl]carbamoyl}-2-(1H-indol-3-yl)ethyl]-2-[(2R)-2-{[(2S)-1-[(2S)-2-amino-4-(methylsulfanyl)butanoyl]pyrrolidin-2-yl]formamido}-3-phenylpropanamido]-5-carbamimidamidopentanamide;

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Specification Technical Data Publications Customer reviews and Q&A
M.F/FormulaC61H87N15O9S
M.W/Mr.1206.5
SequenceOne Letter Code:MPFRWFKPV
Three Letter Code:H-Met-Pro-D-Phe-Arg-D-Trp-Phe-Lys-Pro-Val-NH2
FunctionsNonapeptide-1 is one skin whitening nonapeptide. It can be applied to various kinds of whitening or spot corrective products.
INCINameNonapeptide-1
Dosage20ppm-100ppm
InChIInChI=1S/C61H87N15O9S/c1-37(2)51(52(64)77)74-58(83)50-26-16-31-76(50)60(85)45(23-12-13-28-62)70-55(80)46(33-38-17-6-4-7-18-38)71-56(81)48(35-40-36-68-43-22-11-10-21-41(40)43)72-53(78)44(24-14-29-67-61(65)66)69-54(79)47(34-39-19-8-5-9-20-39)73-57(82)49-25-15-30-75(49)59(84)42(63)27-32-86-3/h4-11,17-22,36-37,42,44-51,68H,12-16,23-35,62-63H2,1-3H3,(H2,64,77)(H,69,79)(H,70,80)(H,71,81)(H,72,78)(H,73,82)(H,74,83)(H4,65,66,67)/t42-,44-,45-,46-,47+,48+,49-,50-,51-/m0/s1
InChI KeyKNFLNGRLKALWRF-LDXSYGEZSA-N
ReferencesMelanostatine 5

1. Immune responses to peptides containing homocitrulline or citrulline in the DR4-transgenic mouse model of rheumatoid arthritis

2. Investigating Potential Interactions Between Neurohypophyseal Peptides, their Drug Analogs, and Coagulation Factor VIII

3. Adipose tissue is a key organ for the beneficial effects of GLP-2 metabolic function

4. Extended exenatide administration enhances lipid metabolism and exacerbates pancreatic injury in mice on a high fat, high carbohydrate diet

5. Effect of Short-Term Desiccation, Recovery Time, and CAPA-PVK Neuropeptide on the Immune System of the Burying Beetle Nicrophorus vespilloides

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