Glutamate Receptor Endocytosis Inhibitor, GluR23Y
Glutamate Receptor Endocytosis Inhibitor, GluR23Y
This GluR23Y peptide was used in ELISA cell-surface assay for the insulin-stimulated endocytosis of native AMPA receptors in cultured hippocampal neurons. GluR23Y prevented any insulin-induced reduction. The blockade of insulin action was observed when the GluR23Y peptide was delivered into neurons by fusing it to the membrane transduction domain of HIV-1.
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| CAT# | X21193 |
| M.W/Mr. | 1092.2 |
| Sequence | One Letter Code: YKEGYNVYG
Three Letter Code: H-Tyr-Lys-Glu-Gly-Tyr-Asn-Val-Tyr-Gly-OH |
| Storage | -20°C |
References | 1. Ahmadian, G. et al. EMBO J. 23, 1040 (2004),
2. Wang, D. et al. J. Biol. Chem. 279, 41267 (2004). |
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