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Leu-Enkephalin-Thr is an endogenous opioid peptide found in the brain. It is a small neuropeptide consisting of five amino acids: Leucine, Enkephalin, and Threonine, which are linked together in a linear sequence.
CAT No: 10-101-249
CAS No: 75644-90-5
Synonyms/Alias: DSLET;75644-90-5;Dislet;DSTLE;2-Ser-thr-leu-enkephalin;Tyr-D-Ser-Gly-Phe-Leu-Thr;(D-Ser2)-Leu-Enkephalin-Thr;(2S,3R)-2-[[(2S)-2-[[(2S)-2-[[2-[[(2R)-2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]-3-hydroxypropanoyl]amino]acetyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]-3-hydroxybutanoic acid;Enkephalin, Ser(2), Leu(5), Thr(6)-;CHEMBL124283;Tyr-ser-gly-phe-leu-thr;Enkephalin-leu, ser(2)-thr-;Leu-enkephalin, ser(2)-thr-;H-Tyr-D-Ser-Gly-Phe-Leu-Thr-OH;Leucine-enkephalin, ser(2)-thr-;YSGFLT;Ser(2)-leu(5)-enkephalin-thr(6);Enkephalin-leu, seryl(2)-threonine-;Tyrosyl-seryl-glycyl-phenylalanyl-leucyl-threonine;[D-Ser2, Leu5, Thr6]-enkephalin;D-Ser2,Thr6-Leucine-enkephalin;DSLET-OH;Ser(2), Leu(5), Thr(6)-enkephalin;D-Ser(2), Leu(5), Thr(6)-enkephalin;enkephalin, D-Ser(2), Leu(5), Thr(6)-;GTPL1609;[D-Ser2,Leu5]Enkephalin-Thr6;DTXSID00997082;CHEBI:176958;L-Threonine, L-tyrosyl-D-serylglycyl-L-phenylalanyl-L-leucyl-;2-{2-[2-(2-{2-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-3-hydroxy-propionylamino}-acetylamino)-3-phenyl-propionylamino]-4-methyl-pentanoylamino}-3-hydroxy-butyric acid;HY-P1332;BDBM50018708;AKOS024456434;L-Threonine, N-(N-(N-(N-(N-L-tyrosyl-D-seryl)glycyl)-L-phenylalanyl)-L-leucyl)-;DA-69156;FS108773;CS-0029454;C20165;H-Tyr-D-Ser-Gly-Phe-Leu-Thr-OH; H-Y(dS)GFLT-OH;Q27077121;(2S,5S,8S,14R,17S)-17-amino-8-benzyl-2-((R)-1-hydroxyethyl)-14-(hydroxymethyl)-18-(4-hydroxyphenyl)-5-isobutyl-4,7,10,13,16-pentaoxo-3,6,9,12,15-pentaazaoctadecan-1-oic acid;N-[14-Amino-5-benzyl-1,4,7,10,13-pentahydroxy-11-(hydroxymethyl)-15-(4-hydroxyphenyl)-2-(2-methylpropyl)-3,6,9,12-tetraazapentadeca-3,6,9,12-tetraen-1-ylidene]threonine;
Chemical Name: (2S,3R)-2-[[(2S)-2-[[(2S)-2-[[2-[[(2R)-2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]-3-hydroxypropanoyl]amino]acetyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]-3-hydroxybutanoic acid
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M.F/Formula | C33H46N6O10 |
M.W/Mr. | 686.8 |
Sequence | One Letter Code:YSGFLT Three Letter Code:H-Tyr-D-Ser-Gly-Phe-Leu-Thr-OH |
Purity | 0.98 |
Long-term Storage Conditions | Soluble to 0.50 mg/ml in sterile water |
InChI | InChI=1S/C33H46N6O10/c1-18(2)13-24(32(47)39-28(19(3)41)33(48)49)37-31(46)25(15-20-7-5-4-6-8-20)36-27(43)16-35-30(45)26(17-40)38-29(44)23(34)14-21-9-11-22(42)12-10-21/h4-12,18-19,23-26,28,40-42H,13-17,34H2,1-3H3,(H,35,45)(H,36,43)(H,37,46)(H,38,44)(H,39,47)(H,48,49)/t19-,23+,24+,25+,26-,28+/m1/s1 |
InChI Key | PKSODCLCMBUCPW-LVNBQDLPSA-N |
Canonical SMILES | CC(C)CC(C(=O)NC(C(C)O)C(=O)O)NC(=O)C(CC1=CC=CC=C1)NC(=O)CNC(=O)C(CO)NC(=O)C(CC2=CC=C(C=C2)O)N |
2. Store-operated Ca2+ entry sustains the fertilization Ca2+ signal in pig eggs
3. Adipose tissue is a key organ for the beneficial effects of GLP-2 metabolic function
4. Autoinhibition and phosphorylation-induced activation of phospholipase C-γ isozymes
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