ω-Conotoxin GVIA is isolated from the venom of the fish-hunting snail Conus geographus. It has a role as a venom, a neurotoxin, a calcium channel blocker, and a marine metabolite.
CAT# | 10-101-281 |
CAS | 106375-28-4 |
M.F/Formula | C120H182N38O43S6 |
M.W/Mr. | 3037.4 |
Sequence | One Letter Code: CKSXGSSCSXTSYNCCRSCNXYTKRCY (Modifications: X = Hyp, Disulfide bridge between 1 - 16, 8 - 19, 15 - 26, Tyr-27 = C-terminal amide) three Letter Code: H-Cys1-Lys-Ser-Hyp-Gly-Ser-Ser-Cys8-Ser-Hyp-Thr-Ser-Tyr-Asn-Cys15-Cys16-Arg-Ser-Cys19-Asn-Hyp-Tyr-Thr-Lys-Arg-Cys26-Tyr-NH2 Hyp: hydroxyproline (Disulfide bonds between Cys1-Cys16, Cys8-Cys19 and Cys15-Cys26) |
Application | N-type calcium channel blocker |
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