BKV (large T antigen)
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| CAT# | PPO-H004 |
| Application | T-cell assays, Immune monitoring, Antigen specific T-cell stimulation, T-cell expansion, Cellular immune response |
| Purity | >70% (HPLC-MS) |
| Areas of Interest | Infection, AIDS, Cancer chemotherapy, Transplantation, Merkel cell carcinoma, PML and BK nephropathy |
| Size | 1 vial containing 15 nmol ( 25μg) per peptide |
SwissProt ID | P14999 |
Format | Freeze dried in amber type glass vial |
NumberOfPeptides | 170 |
Organism | BK polyomavirus |
Specifications | Peptide scan (15mers with 11 aa overlap) |
Protein Length | 691 |
Protein Name | Large T antigen |
References | 1."PepMixTM Peptide Pools for Clinical Applications: T cell therapy for viral infections after hematopoietic stem cell transplant"
Leen et al, Application Note (2012)
2."Differential Patterns of Large Tumor Antigen-Specific Immune Responsiveness in Patients with BK Polyomavirus-Positive Prostate Cancer or Benign Prostatic Hyperplasia". Sais et al., J. Virol. (2012)
3."Polyomavirus BK Large T-antigen Derived Peptide Elicits a HLA-DR Promiscuous and Polyfunctional CD4+ T-cell Response". Clin. Vaccine Immunol. (2011)
4."Nucleofection of DCs to Generate Multivirusspecific T Cells for Prevention or Treatment of Viral Infections in the Immunocompromised Host". Gerdemann et al., Molecular Therapy (2009)
5."Prospective Monitoring of Polyomavirus BK Replication and Impact of Pre-Emptive Intervention in Pediatric Kidney Recipients". Ginevri et al., American Journal of Transplantation (2007) |
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