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ACV 1

ACV 1 is neuronal nicotinic receptor antagonist that displays selectivity for the α9α10 subtype. It can alleviates neuropathic pain in three rat models of human neuropathic pain and accelerate functional recovery of injured neurons.

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CAT No: R0866

CAS No: 740980-24-9

Synonyms/Alias: Conotoxin Vc1.1

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Specification Technical Data Publications Customer reviews and Q&A
M.F/FormulaC71H103N23O25S4
M.W/Mr.1806.98
SequenceGCCSDPRCNYDHPEIC-NH2(Disulfide bridge between Cys2 and Cys8, Cys3 and Cys16)
Labeling TargetNeuronal nicotinic receptor
Purity>99 %
ActivityAntagonist
Solubility-20°C
InChIInChI=1S/C71H103N23O25S4/c1-3-32(2)55-68(117)89-44(56(74)105)27-120-122-30-47-65(114)88-43(26-95)62(111)87-42(23-54(103)104)70(119)94-18-6-8-48(94)66(115)81-36(7-4-16-78-71(75)76)57(106)90-46(29-123-121-28-45(63(112)91-47)80-51(98)24-72)64(113)84-39(21-50(73)97)60(109)83-38(19-33-10-12-35(96)13-11-33)59(108)85-40(22-53(101)102)61(110)86-41(20-34-25-77-31-79-34)69(118)93-17-5-9-49(93)67(116)82-37(58(107)92-55)14-15-52(99)100/h10-13,25,31-32,36-49,55,95-96H,3-9,14-24,26-30,72H2,1-2H3,(H2,73,97)(H2,74,105)(H,77,79)(H,80,98)(H,81,115)(H,82,116)(H,83,109)(H,84,113)(H,85,108)(H,86,110)(H,87,111)(H,88,114)(H,89,117)(H,90,106)(H,91,112)(H,92,107)(H,99,100)(H,101,102)(H,103,104)(H4,75,76,78)
InChI KeyKJQOYUHYAZGPIZ-UHFFFAOYSA-N
BoilingPointN/A
Melting PointN/A

1. Genetic, cellular, and structural characterization of the membrane potential-dependent cell-penetrating peptide translocation pore

2. Olfactory receptor based piezoelectric biosensors for detection of alcohols related to food safety applications

3. Emu oil in combination with other active ingredients for treating skin imperfections

4. Exosomes-mediated Transfer of miR-125a/b in Cell-to-cell Communication: A Novel Mechanism of Genetic Exchange in the Intestinal Microenvironment

5. Novel Peptide-Based PD1 Immunomodulators Demonstrate Efficacy in Infectious Disease Vaccines and Therapeutics

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