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Acetyl Hexapeptide-1 is the reaction product of Alanine, arginine, histidine, leucine, phenylalanine and tryptophane hexapeptide with acetic acid. It activates the regulation of melanin synthesis, relating the protection of natural light and inflammatory regulator.
CAT No: CPC1615
CAS No: 448944-47-6
Synonyms/Alias: Acetyl hexapeptide-1;Melitane;448944-47-6;Melitane (Acetyl Hexapeptide-1);(2S)-2-acetamido-N-[(2S)-1-[[(2S)-1-[[(2R)-1-[[(2S)-1-[[(2S)-1-amino-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]amino]-1-oxopropan-2-yl]hexanamide;Stellight;Melitane?;Acetyl hexapeptide 1;Melitane GL 200;UNII-49ZWR266MZ;Melitane(AcetylHexapeptide-1);49ZWR266MZ;WPIQUSRULDNCKM-IFSWANACSA-N;HY-P5220;448744-47-6;DA-70500;CS-0857349;
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M.F/Formula | C43H59N13O7 |
M.W/Mr. | 870 |
Sequence | One Letter Code:XAHFRW Three Letter Code:Ac-Nle-Ala-His-D-Phe-Arg-Trp-NH2 |
Application | Acetyl Hexapeptide-1 works as a bio-α-MSH peptide analog. It stimulates hair pigmentation, darkens hair and reverses the gray hair process. It also can help repair DNA damage caused by UV exposure and reduce the skin erythema. |
Long-term Storage Conditions | Practically insoluble (0.076 g/L) (25 ºC) |
Shipping Condition | Room temperature in continental US; may vary elsewhere. |
InChI | InChI=1S/C43H59N13O7/c1-4-5-15-32(52-26(3)57)39(60)51-25(2)38(59)55-36(21-29-23-47-24-50-29)42(63)56-35(19-27-12-7-6-8-13-27)41(62)53-33(17-11-18-48-43(45)46)40(61)54-34(37(44)58)20-28-22-49-31-16-10-9-14-30(28)31/h6-10,12-14,16,22-25,32-36,49H,4-5,11,15,17-21H2,1-3H3,(H2,44,58)(H,47,50)(H,51,60)(H,52,57)(H,53,62)(H,54,61)(H,55,59)(H,56,63)(H4,45,46,48)/t25-,32-,33-,34-,35+,36-/m0/s1 |
InChI Key | WPIQUSRULDNCKM-IFSWANACSA-N |
3. The spatiotemporal control of signalling and trafficking of the GLP-1R
5. TMEM16F and dynamins control expansive plasma membrane reservoirs
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