* Please kindly note that our products and services can only be used to support research purposes (Not for clinical use).
At Creative Peptides, we have been designing, synthesizing and applying peptide library technology for many years. We provide overlapping peptide library services that will be tailored to specific research issues.
The design of overlapping peptide library is mainly used for whole protein scanning. The head-to-tail peptide matrix is a common method for screening linear or continuous epitopes. The design of this peptide library is mainly determined by two key parameters, peptide length and offset number. The design is gradually intercepted from the N-terminal to C-terminal of the target protein, there is likely to be a orphan peptide. We generally transfer one or more amino acids from the N-terminal to maintain the same length.
Choosing the appropriate step and peptide length can reduce the experimental cost and maximize the value of the data. The step is usually designed as a third of the peptide length. Long peptides contain more epitopes, but such peptides are generally difficult to synthesize and contain fewer peptides in the library. Short peptides are easier to synthesize and cheaper, but have fewer epitopes per peptide.
Creative Peptides's overlapping peptide library can be designed according to customers' requirements and future experimental purposes, and provide personal services such as peptide library design consultation and peptide library design guidance according to customers' practical problems.
References
Creative Peptides has accumulated a huge library of peptide knowledge including frontier peptide articles, application of peptides, useful tools, and more!
An overview of Tripeptide-10 Citrulline Signal oligopeptides are commonly synthesized from portions of EMPs and from natural ...
P11 (HSDVHK) is a novel peptide ligand containing a PDZ-binding motif (Ser-Asp-Val) with high affinity to integr ...
Astressin 2B is a peptidic antagonist to CRF2 (corticotrophin-releasing factor 2) receptor with structure of cyc ...
Peptides are compounds formed by linking α-amino acids by peptide bonds, and are intermediate products of proteolysis. They a ...
Orexin A (OXA) and orexin B (OXB) are hypothalamic neuropeptides discovered in 1998, which bind to two G-protein ...