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Tet-20, is a synthetic cathelicidin-derived peptide. It was tested as infection-resistant coating for medical devices. When tethered on an implant surface Tet-20 exhibited broad antimicrobial activities both in vivo and in vitro. It can stop biofilm formation and appears to be non-toxic to eukaryotic cells.
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M.W/Mr. | 1769.3 |
Sequence | One Letter Code: KRWRIRVRVIRKC Three Letter Code: H-Lys-Arg-Trp-Arg-Ile-Arg-Val-Arg-Val-Ile-Arg-Lys-Cys-OH |
Long-term Storage Conditions | Tet-20 antimicrobial peptide is freely soluble in H2O |
References | 1. Riool M. et al., Front Chem 5:63 (2017) 2. Sobczak M. et al., Molecules 18(11), 14122-14137 (2013) |
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