S3 Fragment, ADF/cofilin
This peptide contains the unique amino-terminal phosphorylation site of Xenopus ADF/cofilin, the LIM kinase (LIMK) phosphorylation site. LIMK1 is a key regulator of the actin cytoskeleton through its phosphorylation of ADF/cofilin at serine-3 for inactivation. This peptide is a fragment of the S3 peptide containing the serine-3 sequence of ADF/cofilin that has been widely used as an effective competitive inhibitor of LIMK1.
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| CAT# | P75018 |
| M.W/Mr. | 1698 |
| Sequence | One Letter Code: MASGVMVSDDVVKVFN
Three Letter Code: H-Met-Ala-Ser-Gly-Val-Met-Val-Ser-Asp-Asp-Val-Val-Lys-Val-Phe-Asn-OH |
| Storage | -20°C |
References | Wen, Z. et al. J. Cell Biol. 178, 107 (2007). |
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