Desamidation of neuropeptide Y suppresses almost all of NPY effects.
CAT# | N05027 |
CAS | 99575-89-0 |
M.F/Formula | C189H284N54O58S |
M.W/Mr. | 4272.73 |
Sequence | H-Tyr-Pro-Ser-Lys-Pro-Asp-Asn-Pro-Gly-Glu-Asp-Ala-Pro-Ala-Glu-Asp-Met-Ala-Arg-Tyr-Tyr-Ser-Ala-Leu-Arg-His-Tyr-Ile-Asn-Leu-Ile-Thr-Arg-Gln-Arg-Tyr-OH |
Biological Activity | Neuropeptide Y (NPY) is a neuropeptide abundantly distributed throughout the central and peripheral nervous systems that plays a major role in controlling appetite, blood pressure, cardiac contractility, and intestinal secretion. The free acid form of NPY is less potent than NPY at inhibiting forskolin-induced cAMP accumulation in cultured bovine adrenal chromaffin cells. |
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