Neuropeptide Y, free acid, human, rat

Desamidation of neuropeptide Y suppresses almost all of NPY effects.

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CAT#N05027
CAS99575-89-0
M.F/FormulaC189H284N54O58S
M.W/Mr.4272.73
SequenceH-Tyr-Pro-Ser-Lys-Pro-Asp-Asn-Pro-Gly-Glu-Asp-Ala-Pro-Ala-Glu-Asp-Met-Ala-Arg-Tyr-Tyr-Ser-Ala-Leu-Arg-His-Tyr-Ile-Asn-Leu-Ile-Thr-Arg-Gln-Arg-Tyr-OH
Biological ActivityNeuropeptide Y (NPY) is a neuropeptide abundantly distributed throughout the central and peripheral nervous systems that plays a major role in controlling appetite, blood pressure, cardiac contractility, and intestinal secretion. The free acid form of NPY is less potent than NPY at inhibiting forskolin-induced cAMP accumulation in cultured bovine adrenal chromaffin cells.
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