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cGMP Dependent Kinase Inhibitor Peptide

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CAT#	R0846
CAS	82801-73-8
M.F/Formula	C38H74N18O10
M.W/Mr.	943.12
Sequence	Arg-Lys-Arg-Ala-Arg-Lys-Glu
Application	Competitive inhibitor of cGMP-dependent protein kinase (PKG); analog of a substrate peptide corresponding to a phosphorylation site of histone H2B. Competes with synthetic substrates (Ki = 86 mM) but does not inhibit phosphorylation of intact histones by PKG. Inhibits phosphorylation of intact histones by PKA.
Purity	>98 %

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R1819	Cyclic citrullinated peptide	Inquiry
R1510	Melanin Concentrating Hormone, salmon	Inquiry
R1126	[Nle11]-Substance P	Inquiry
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R1190	Amylin, amide, rat	Inquiry

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Storage	-20°C
Long-term Storage Conditions	-20 °C
InChI	InChI=1S/C38H74N18O10/c1-21(29(59)52-26(13-8-20-50-38(46)47)33(63)54-24(11-3-5-17-40)34(64)56-27(35(65)66)14-15-28(57)58)51-31(61)25(12-7-19-49-37(44)45)55-32(62)23(10-2-4-16-39)53-30(60)22(41)9-6-18-48-36(42)43/h21-27H,2-20,39-41H2,1H3,(H,51,61)(H,52,59)(H,53,60)(H,54,63)(H,55,62)(H,56,64)(H,57,58)(H,65,66)(H4,42,43,48)(H4,44,45,49)(H4,46,47,50)/t21-,22-,23-,24-,25-,26-,27-/m0/s1
InChI Key	OUKSKNTVYYVIMZ-DUJSLOSMSA-N
Isomeric SMILES	C[C@@H](C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(=O)O)C(=O)O)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCN=C(N)N)N
BoilingPoint	N/A
Melting Point	N/A