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This is a myristoylated form of Autocamtide-3-Derived Inhibitory Peptide (AC3-I), a highly specific inhibitor of Calmodulin-Dependent Protein Kinase ll (CaMKII) that is resistant to proteolysis. AC3-I is derived from Autocamtide-3, a substrate for CaMKII, with the Thr-9 phosphorylation site substituted with Ala.
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M.W/Mr. | 1689.2 |
Sequence | One Letter Code: Myr-KKALHRQEAVDAL Three Letter Code: Myr-Lys-Lys-Ala-Leu-His-Arg-Gln-Glu-Ala-Val-Asp-Ala-Leu-OH |
References | Chen, HX. et al. J Neurophysiol 85, 1368 (2001). |
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