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[Asp371]-Tyrosinase (369-377), human

Tyrosinase 369-377, human is a HLA-A2.1-restricted epitope derived from tyrosinase, has been used to develop tumor-targeted vaccines with mixed efficacy.

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CAT No: R1116

CAS No: 168650-46-2

Synonyms/Alias: 168650-46-2;[Asp371]-Tyrosinase (369-377), human;2-[[5-amino-2-[[2-[[2-[[2-[[2-[[2-[[2-[[2-amino-3-(4-hydroxyphenyl)propanoyl]amino]-4-methylsulfanylbutanoyl]amino]-3-carboxypropanoyl]amino]acetyl]amino]-3-hydroxybutanoyl]amino]-4-methylsulfanylbutanoyl]amino]-3-hydroxypropanoyl]amino]-5-oxopentanoyl]amino]-3-methylbutanoic acid;2,2,2-trifluoroacetic acid;(Asp371)-Tyrosinase (369-377) (human) acetate salt;168650-46-2(free basis);H-Tyr-Met-Asp-Gly-Thr-Met-Ser-Gln-Val-OH; H-YMDGTMSQV-OH;YMDGTMSQV;Asp371;Tyrosinase 369-377;FA73646;DA-69124;FA109106;FA110240;[Asp371] Tyrosinase(369-377), human;(Asp371)-Tyrosinase (369-377) (human) trifluoroacetate salt;

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M.F/FormulaC44H67F3N10O18S2
M.W/Mr.1145.2
SequenceOne Letter Code:YMDGXMSQV
Three Letter Code:H-DL-Tyr-DL-Met-DL-Asp-Gly-DL-xiThr-DL-Met-DL-Ser-DL-Gln-DL-Val-OH.TFA
Areas of InterestAntigen-presenting Cells; Cancer Research
Source#Homo sapiens (human)
Restricting HLAHLA-A2
InChIInChI=1S/C42H66N10O16S2.C2HF3O2/c1-20(2)33(42(67)68)52-39(64)25(10-11-30(44)56)47-40(65)29(19-53)50-38(63)27(13-15-70-5)48-41(66)34(21(3)54)51-31(57)18-45-36(61)28(17-32(58)59)49-37(62)26(12-14-69-4)46-35(60)24(43)16-22-6-8-23(55)9-7-22;3-2(4,5)1(6)7/h6-9,20-21,24-29,33-34,53-55H,10-19,43H2,1-5H3,(H2,44,56)(H,45,61)(H,46,60)(H,47,65)(H,48,66)(H,49,62)(H,50,63)(H,51,57)(H,52,64)(H,58,59)(H,67,68);(H,6,7)
InChI KeyTWALUFAMCVRLBU-UHFFFAOYSA-N
ReferencesZhigang Wang; Cell Transplant 2015
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