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PBP 10

Selective and cell-permeable antagonist of formyl peptide receptor 2 (FPR2), which selectively inhibits fpr2-mediated nadph oxidase activity, but has no effect on fpr1 signaling in neutrophils.

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CAT#	R0987
CAS	794466-43-6
M.F/Formula	C84H126N24O15
M.W/Mr.	1712.1
Sequence	QRLFQVKGRR(Gln-1 = Rhodamine-B)
Labeling Target	Formyl peptide receptor 2 (FPR2)
Appearance	White lyophilised solid
Purity	>98%
Activity	Antagonist

CAT#	Product Name	Inquiry
R1150	Ac-MBP 1-11	Inquiry
HB00027	Z-ATAD-FMK	Inquiry
R1729	Transportan	Inquiry
R1396	Gp100 619-627	Inquiry
PI-002	Angiopep-2	Inquiry

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Storage	-20°C
InChI	InChI=1S/C84H126N24O15/c1-9-107(10-2)51-31-33-55-65(45-51)123-66-46-52(108(11-3)12-4)32-34-56(66)70(55)53-25-16-17-26-54(53)72(112)99-60(35-37-67(86)109)76(116)100-59(29-21-41-95-83(90)91)75(115)104-63(43-48(5)6)78(118)105-64(44-50-23-14-13-15-24-50)79(119)101-61(36-38-68(87)110)77(117)106-71(49(7)8)80(120)102-57(27-18-19-39-85)73(113)97-47-69(111)98-58(28-20-40-94-82(88)89)74(114)103-62(81(121)122)30-22-42-96-84(92)93/h13-17,23-26,31-34,45-46,48-49,57-64,71H,9-12,18-22,27-30,35-44,47,85H2,1-8H3,(H26-,86,87,88,89,90,91,92,93,94,95,96,97,98,99,100,101,102,103,104,105,106,109,110,111,112,113,114,115,116,117,118,119,120,121,122)/t57-,58-,59-,60-,61-,62-,63-,64-,71-/m0/s1
InChI Key	OIOWMSSANHIUTR-NVWDZAHRSA-N
Isomeric SMILES	CCN(CC)C1=CC2=C(C=C1)C(=C3C=CC(=[N+](CC)CC)C=C3O2)C4=CC=CC=C4C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC5=CC=CC=C5)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)NCC(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCNC(=N)[NH-])C(=O)O