C 21 is a selective inhibitor of protein arginine methyltransferase 1 (PRMT1) (IC50 = 1.8 μM), which displays five-fold selectivity for PRMT1 over PRMT6 and >250-fold selectivity over PRMT3 and CARM1.
CAT# | R0979 |
CAS | 1229236-78-5 |
M.F/Formula | C90H161ClN36O24 |
M.W/Mr. | 2166.94 |
Sequence | SGXGKGGKGLGKGGAKRHRKV(Modifications: Ser-1 = N-terminal Ac, X = N5-(2-Chloro-1-iminoethyl)]-Orn) |
Labeling Target | Protein arginine methyltransferase 1 (PRMT1) |
Appearance | White lyophilised solid |
Purity | >98% |
Activity | Inhibitor |
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