C 21

C 21 is a selective inhibitor of protein arginine methyltransferase 1 (PRMT1) (IC50 = 1.8 μM), which displays five-fold selectivity for PRMT1 over PRMT6 and >250-fold selectivity over PRMT3 and CARM1.

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CAT#R0979
CAS1229236-78-5
M.F/FormulaC90H161ClN36O24
M.W/Mr.2166.94
SequenceSGXGKGGKGLGKGGAKRHRKV(Modifications: Ser-1 = N-terminal Ac, X = N5-(2-Chloro-1-iminoethyl)]-Orn)
Labeling TargetProtein arginine methyltransferase 1 (PRMT1)
AppearanceWhite lyophilised solid
Purity>98%
ActivityInhibitor
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