ATN-161 is a novel peptide antagonist of integrin α5β1. ATN-161 selectively binds to and blocks the receptor for integrin α5β1, thereby preventing integrin alpha5beta1 binding. This receptor blockade may result in inhibition of endothelial cell-cell interactions, endothelial cell-matrix interactions, angiogenesis, and tumor progression. It has potential antineoplastic activity.
CAT# | R0965 |
CAS | 262438-43-7 |
Synonyms/Alias | ATN161; ATN 161; ATN-161; AcPHSCNNH2 |
M.F/Formula | C23H35N9O8S |
M.W/Mr. | 597.65 |
Sequence | Ac-PHSCN-NH2 |
Labeling Target | Integrin α5β1 |
Appearance | white solid powder |
Purity | >98% (or refer to the Certificate of Analysis) |
Activity | Antagonist |
Areas of Interest | Cancer |
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