Amylin, human amidated
Amylin, amide, human, a 37-amino acid polypeptide, is a pancreatic hormone cosecreted with insulin that exerts unique roles in metabolism and glucose homeostasis. Amylin, amide, human inhibits glucagon secretion, delays gastric emptying, and acts as a satiety agent.
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| CAT# | HB00087 |
| Chemical Structure |  |
| CAS | 122384-88-7 |
| Synonyms/Alias | DAP amide, human |
| M.F/Formula | C165H261N51O55S2 |
| M.W/Mr. | 3903.28 |
| Sequence | One Letter Code: KCNTATCATQRLANFLVHSSNNFGAILSSTNVGSNTY-NH2 (Disulfide bridge: Cys2-Cys7)
Three Letter Code: Lys-Cys-Asn-Thr-Ala-Thr-Cys-Ala-Thr-Gln-Arg-Leu-Ala-Asn-Phe-Leu-Val-His-Ser-Ser-Asn-Asn-Phe-Gly-Ala-Ile-Leu-Ser-Ser-Thr-Asn-Val-Gly-Ser-Asn-Thr-Tyr-NH2 (Disulfide bridge: Cys2-Cys7) |
| Appearance | White to off-white lyophilized solid |
| Biological Activity | Endogenous peptide agonist for amylin, calcitonin, CGRP and adrenomedullin receptors. Inhibits glucagon secretion, delays gastric emptying and acts as a satiety agent. Displays glucose lowering effects in vivo. |
| Storage | Desiccate at -20°C |
Solubility | Soluble to 10 mg/ml in DMSO |
Shipping Condition | Room temperature in continental US; may vary elsewhere. |
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