Search

AMY-101

AMY-101 is a peptidic inhibitor of the central complement component C3.

Online Inquiry

Specification Technical Data Related Products Customer reviews and Q&A Useful Tools Publications
CAT#R1905
CAS1427001-89-5
Synonyms/AliasAMY-101; AMY 101; AMY101;Compstatin 40; CP40; CP 40; CP-40
Chemical Name2-[(4R,7S,10S,13S,19S,22S,25S,28S,31S,34R)-34-[[(2S,3S)-2-[[(2R)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]-3-methylpentanoyl]amino]-4-[[(2S,3S)-1-amino-3-methyl-1-oxopentan-2-yl]-methylcarbamoyl]-25-(3-amino-3-oxopropyl)-7-(3-carbamimidamidopropyl)-10-(1H-imidazol-5-ylmethyl)-19-(1H-indol-3-ylmethyl)-13,17-dimethyl-28-[(1-methylindol-3-yl)methyl]-6,9,12,15,18,21,24,27,30,33-decaoxo-31-propan-2-yl-1,2-dithia-5,8,11,14,17,20,23,26,29,32-decazacyclopentatriacont-22-yl]acetic acid
M.F/FormulaC83H117N23O18S2
M.W/Mr.1789.11
SequenceOne Letter Code: YICVXQDWGAHRCI
Three Letter Code: H-D-Tyr-Ile-Cys(1)-Val-Trp(Me)-Gln-Asp-Trp-Sar-Ala-His-Arg-Cys(1)-N(Me)Ile-NH2
AppearanceSolid powder
ActivityInhibitor
Biological ActivityAMY-101 TFA (Cp40 TFA) is a peptidic inhibitor of the central complement component C3 (KD: 0.5 nM). It shows a favorable anti-inflammatory activity in models with COVID-19 severe pneumonia with systemic hyper inflammation.
Quick Inquiry
×
If you have any peptide synthesis requirement in mind, please do not hesitate to contact us at . We will endeavor to provide highly satisfying products and services.
Customer Support & Price Inquiry

* Please kindly note that our products and services can only be used to support research purposes (Not for clinical use).

Recommended Services

Peptide Synthesis Services

Custom Conjugation Service

Peptide PEGylation

Unusual and Non-natural Amino Acids Modification

cGMP Peptide Service

Peptide CDMO

Peptide API Development

Resource

Creative Peptides has accumulated a huge library of peptide knowledge including frontier peptide articles, application of peptides, useful tools, and more!

Function of NoxA1ds in Colon Cancer

 NoxA1ds is derived from a peptide whose structure is based on a short sequence of an essential Nox subunit. It b ...

Definition, classification, and benefits of collagen peptides

What are collagen peptides? Collagen peptides are repair collagen, and the protein slowly decreases with age. It can be see ...

Function of corticotropin in the diagnosis of adrenocortical function

 Corticotropin (ACTH or adrenocorticotropic hormone) is a linear coupling of 39 amino acid residues and an import ...

The effect of Sincalide on gastric movement

 Sincalide is a brain and intestinal skin with a variety of physiological effects. It is widely distributed in th ...

An antiplatelet drug of the glycoprotein IIb/IIIa inhibitor class - Eptifibatide Acetate

  Eptifibatide acetate is a white or white-off powder, soluble in water and freely soluble in 1% acetic in water, ...

Contact Us

USA

Address:

Tel: |

Email:

Germany

Address:

Copyright © 2024 Creative Peptides. All rights reserved.