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UP_P62804

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CAT#X19200
SequenceALKRQGRTLYGFGG
FunctionsCore component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodelling. Osteogenic growth peptide (OGP) stimulates osteogenesis and hematopoiesis.
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