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UP_P0C1V7

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CAT#X18078
SequenceGGCCSHPACAANNQDYC
FunctionsAlpha-conotoxins act on postsynaptic membranes, they bind to the nicotinic acetylcholine receptors (nAChR) and thus inhibit them. Synthetic AnIB blocks mammalian alpha3beta2 nAChRs (IC(50)=0.3 nM), and alpha7 nAChRs (IC(50)=76 nM). Synthetic AnIA blocks mammalian alpha3beta2 nAChRs (IC(50)=0.2 nM).
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