NFF-3
NFF-3 is hydrolyzed rapidly by MMP-3 (kcat/Km = 218,000 s-1 M-1) and very slowly by MMP-9 (kcat/Km = 10,100 s-1 M-1), but no significant hydrolysis by MMP-1 and MMP-2. It is one of the few synthetic substrates selectively hydrolyzed by certain members of the MMP family and thus has important applications for the differentiation of MMP-3 activity from that of other MMPs. Abs/Em = 325/393 nm.
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| CAT# | X21176 |
| M.W/Mr. | 1675.9 |
| Sequence | One Letter Code: Mca-RPKPVE-Nva-WR-K(Dnp)-NH2
Three Letter Code: Mca-Arg-Pro-Lys-Pro-Val-Glu-Nva-Trp-Arg-Lys(Dnp)-NH2 |
| Storage | -20°C |
References | 1. Bremer, C. et al. Acad. Radiol. 9 Suppl 2, S314 (2002);
2. Nagase, H. et al. J. Biol. Chem. 269, 20952 (1994). |
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