Caspase Inhibitor I
Z-VAD(OMe)-FMK (Z-Val-Ala-Asp(OMe)-FMK) is a cell-permeable and irreversible pan-caspase inhibitor. Z-VAD(OMe)-FMK is an ubiquitin carboxy-terminal hydrolase L1 (UCHL1) inhibitor. Z-VAD(OMe)-FMK irreversibly modifies UCHL1 by targeting the active site of UCHL1.
Online Inquiry
| CAT# | R1807 |
| Chemical Structure |  |
| CAS | 187389-52-2 |
| Synonyms/Alias | Z-VAD (OMe)-FMK |
| M.F/Formula | C22H30FN3O7 |
| M.W/Mr. | 467.49 |
| Sequence | One Letter Code: ZVA-D(OMe)-FMK
Three Letter Code: Z-Val-Ala-Asp(OMe)-CH₂F |
| Labeling Target | Pan-caspase |
| Application | Z-VAD-FMK is an irreversible, cell-permeable, broad-spectrum caspase inhibitor. |
| Appearance | White solid |
| Purity | >98.0% |
| Activity | Inhibitor |
| Areas of Interest | Cancer |
| Source# | Synthetic |
Storage | Desiccate at -20°C |
Solubility | Soluble in DMSO |
Shipping Condition | Room temperature in continental US; may vary elsewhere. |
Long-term Storage Conditions | -20 °C |
InChI | InChI=1S/C22H30FN3O7/c1-13(2)19(26-22(31)33-12-15-8-6-5-7-9-15)21(30)24-14(3)20(29)25-16(17(27)11-23)10-18(28)32-4/h5-9,13-14,16,19H,10-12H2,1-4H3,(H,24,30)(H,25,29)(H,26,31)/t14-,16-,19-/m0/s1 |
InChI Key | MIFGOLAMNLSLGH-QOKNQOGYSA-N |
Isomeric SMILES | C[C@@H](C(=O)N[C@@H](CC(=O)OC)C(=O)CF)NC(=O)[C@H](C(C)C)NC(=O)OCC1=CC=CC=C1 |
BoilingPoint | 732.4±60.0 °C at 760 mmHg |
Melting Point | N/A |
Write a review
Ask a question
My Review for Caspase Inhibitor I
Required fields are marked with *
×
Ask a Question for Caspase Inhibitor I
Required fields are marked with *
×
If you have any peptide synthesis requirement in mind, please do not hesitate to contact us at . We will endeavor to provide highly satisfying products and services.
