BMAP-18
BMAP-18 is a truncated form of the antimicrobial peptide BMAP-271. Bovine myeloid antimicrobial peptide-27(BMAP-27) belongs to the Cathelicidin family of peptides which displays rapid bactericidal activity against Staphylococcus aureus, Streptococcus uberis, and Escherichia coli. BMAP-27 is cytotoxic to human erythrocytes and neutrophils, although at higher than microbicidal concentrations1-3. BMAP-18 displays much higher cell selectivity as compared to parental BMAP-27 because of their decreased hemolytic activity and retained antimicrobial activity.
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| CAT# | AF3341 |
| Synonyms/Alias | Bovine myeloid antimicrobial peptide-18 |
| M.W/Mr. | 2343 |
| Sequence | One Letter Code: GRFKRFRKKFKKLFKKLS
Three Letter Code: Gly-Arg-Phe-Lys-Arg-Phe-Arg-Lys-Lys-Phe-Lys-Lys-Leu-Phe-Lys-Lys-Leu-Ser |
| Storage | -20°C |
Solubility | BMAP-18 antimicrobial peptide is freely soluble in H2O |
References | 1. Haines L.R et al.,PLoS Negl Trop Dis.3(2) 373 (2009)
2. Cheng K et al mBio 7 01418-16 (2016)
3. Lee E.K et al Peptides 32(6), 1123-1130 (2011) |
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