Deslorelin Acetate is a potent GnRH analog peptide for fertility control research. Order Deslorelin peptide from a professional peptide supplier for veterinary applications.
CAT No: 10-101-10
CAS No:57773-65-6 (net)
Synonyms/Alias:deslorelin acetate;82318-06-7;Deslorelin (acetate);UNII-679007NR5C;679007NR5C;SUPRELORIN;DTXSID1046683;DTXCID9026683;82318-06-7 (acetate);1642579-30-3;(D-TRP(SUP 6),DES-GLY(SUP 10))-LH-RH ETHYLAMIDE ACETATE;(S)-1-((3S,6S,9S,12S,15R,18S,21S)-3-((1H-imidazol-5-yl)methyl)-6,15-bis((1H-indol-3-yl)methyl)-21-(3-((diaminomethylene)amino)propyl)-12-(4-hydroxybenzyl)-9-(hydroxymethyl)-18-isobutyl-1,4,7,10,13,16,19-heptaoxo-1-((S)-5-oxopyrrolidin-2-yl)-2,5,8,11,14,17,20-heptaazadocosan-22-oyl)-N-ethylpyrrolidine-2-carboxamide acetate;5-OXO-L-PROLYL-L-HISTIDYL-L-TRYPTOPHYL-L-SERYL-L-TYROSYL-D-TRYPTOPHYL-L-LEUCYL-L-ARGINYL-N-ETHYL-L-PROLINAMIDE ACETATE;DESLORELIN ACETATE (EMA EPAR VETERINARY);DESLORELIN ACETATE [EMA EPAR VETERINARY];NCGC00167516-01;Suprelorin F;Bachem 9022 Acetate;SCHEMBL205614;DESLORELIN ACETATE [MI];CHEMBL2357192;DESLORELIN ACETATE [WHO-DD];Tox21_112514;MFCD09842868;AKOS030485982;DESLORELIN ACETATE [GREEN BOOK];FD41614;TS-10606;CAS-82318-06-7;NS00134281;Q27264098;(Des-Gly10,D-Trp6,Pro-NHEt9)-LHRH High acetate salt;Deslorelin acetate 100 microg/mL in Acetonitrile:Methanol;Deslorelin acetate; 1-9-Luteinizing hormone-releasing factor (swine), 6-D-tryptophan-9-(N-ethyl-L-prolinamide)-, acetate (1:?); 6-D-Tryptophan-9-(N-ethyl-L-prolinamide)-10-deglycinamide-luteinizing hormone-releasing factor (pig) acetate (salt); 6-D-Trypto;L-Prolinamide, 5-oxo-L-prolyl-L-histidyl-L-tryptophyl-L-seryl-L-tyrosyl-D-tryptophyl-L-leucyl-L-arginyl-N-ethyl-,?acetate (1:1);
Chemical Name:acetic acid;(2S)-N-[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2R)-1-[[(2S)-1-[[(2S)-5-(diaminomethylideneamino)-1-[(2S)-2-(ethylcarbamoyl)pyrrolidin-1-yl]-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]-5-oxopyrrolidine-2-carboxamide
Deslorelin Acetate is a synthetic peptide analog of gonadotropin-releasing hormone (GnRH), structurally designed to mimic and modulate the activity of endogenous GnRH in biological systems. As a decapeptide, it is characterized by its high binding affinity and prolonged receptor interaction, making it a valuable tool for probing the hypothalamic-pituitary-gonadal (HPG) axis in various model organisms. Its capacity to influence gonadotropin secretion with greater potency and duration than natural GnRH has established its significance in endocrinological research, reproductive biology, and peptide pharmacology studies. The robust biochemical profile and receptor specificity of Deslorelin Acetate underpin its widespread adoption in laboratory investigations focused on neuroendocrine regulation and peptide-receptor dynamics.
Endocrine Function Studies: Deslorelin Acetate is extensively utilized in research examining the regulation of pituitary gonadotropin release. By acting as a potent GnRH receptor agonist, it enables controlled stimulation or suppression of luteinizing hormone (LH) and follicle-stimulating hormone (FSH) secretion in in vitro and in vivo systems. This facilitates the dissection of feedback mechanisms within the HPG axis and supports the development of experimental models for reproductive hormone modulation, which are essential for advancing the understanding of endocrine signaling pathways.
Reproductive Biology Research: In studies of reproductive physiology, Deslorelin analogs serve as precise modulators of gonadal function. Their ability to induce or inhibit ovulation and spermatogenesis in animal models makes them indispensable for elucidating the molecular events underlying gametogenesis and gonadal steroidogenesis. Researchers employ these peptide tools to synchronize estrous cycles, investigate fertility control strategies, and explore the temporal dynamics of reproductive hormone cascades under various experimental conditions.
Peptide-Receptor Interaction Analysis: The molecular structure and high receptor affinity of Deslorelin Acetate render it a preferred ligand for characterizing GnRH receptor binding kinetics and downstream signaling events. Using radiolabeled or fluorescently tagged derivatives, investigators can map receptor distribution, quantify binding affinities, and delineate G-protein-coupled receptor (GPCR) activation profiles. Such studies are crucial for drug discovery efforts targeting the GnRH receptor and for elucidating the structural determinants of peptide-receptor specificity.
Peptide Synthesis and Analytical Method Development: As a well-characterized synthetic decapeptide, Deslorelin Acetate is frequently employed as a reference standard in peptide synthesis optimization and quality control protocols. Its defined sequence and bioactivity facilitate the calibration of chromatographic and mass spectrometric methods, enabling accurate quantification and purity assessment of related peptide products. This application supports both academic and industrial laboratories engaged in peptide manufacturing, analytical validation, and method development for complex peptide therapeutics.
Comparative Endocrinology and Evolutionary Studies: The use of Deslorelin and its analogs extends to comparative investigations across species, where it serves as a tool for probing the conservation and divergence of GnRH signaling pathways. By assessing its effects in diverse vertebrate models, researchers can explore evolutionary adaptations in reproductive endocrinology, receptor isoform functionality, and species-specific regulatory mechanisms. These insights contribute to a broader understanding of hormone action and the evolution of peptide signaling systems in the animal kingdom.
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