Background Peptide drugs, as a type of pharmaceutical with molecular weight between small molecule chemical drugs and biopolymers, provide more options for medicinal chemists and have become a hot research …
Background In recent years, more and more studies have described the antioxidant capacity of plant protein-derived peptides. Plant proteins are considered a new source of antioxidant peptides that can not …
Antiviral drugs Antiviral drugs are a class of drugs used to treat viral infections. While most antiviral drugs target specific viruses, broad-spectrum antivirals are effective against multiple viruses. Most of …
The gastrointestinal tract is the largest immune organ in the human body. The gastrointestinal tract refers to the digestive tract from the gastric pylorus to the anus, including the stomach, …
Intranasal (IN, intranasal) delivery of peptides has received considerable attention as a potential non-invasive delivery route through which peptide drugs can easily enter systemic circulation. Nasal delivery offers several advantages, …
Given the rapid metabolism and short action time of peptide drugs, pharmaceutical chemists have explored a variety of methods to improve the metabolic stability of the peptide. The main recognition …
Background Recently, FDA approved the dual immunotherapy treatment for hepatocellular carcinoma with Astrazeneca’s Imjudo (tremelimumab) combined with Imfinzi (durvalumab), marking the second time of this year for the authoritative approval …
The effect of drugs is achieved by interfering with the pathogenic process by binding between drug molecules and receptors. The binding between the drug and the receptor protein, in addition …
Peptide-based drug design has attracted much interest with the rapid growth of bioinformatics knowledge related to peptides and proteins. In the past, peptide-based drugs were not widely used due to …
Classes of Cell-Penetrating Peptides There are many types of cell-penetrating peptides (CPPs), and their classification is based on physicochemical properties, sources, intake mechanisms, and biomedical applications. There is no unified …