* Please kindly note that our products and services can only be used to support research purposes (Not for clinical use).
As a leading supplier of bioactive peptides, we provide comprehensive services for glycosylated peptide development and production from mg to kg quantities to meet your project needs.
Glycosylation is the most common post-translational modification of proteins in eukaryotic cells. As one of the most important recognition signals, glycosylated proteins and peptides are involved in much intracellular communication, such as apoptosis, cell growth regulation, infection process, and immunological differentiation.
Protein glycosylation can be categorized into four main categories mainly according to various glycosidic linkages between the amino acid and the sugar, including
Figure 1: Structures of N-glycans and O-glycans.
Creative peptides recognizes that all our clients have specific and unique requirements. We provide common monosaccharide, disaccharide and polysaccharide services. Other glycosylation modifications (sialic acid, fucose, etc.) can also be performed on the main chain and side chain of the polypeptide.
Glucose
Name | CAS | Formula | Acetate Groups Removed |
---|---|---|---|
Fmoc-L-Ser((Ac)3-β-D-GlcNAc)-OH | 160067-63-0 | C32H36N2O13 | Yes&No |
Fmoc-L-Thr((Ac)3-β-D-GlcNAc)-OH | 160168-40-1 | C33H38N2O13 | Yes&No |
FMoc-Asn(β-D-GlcNAc(Ac)3)-OH | 131287-39-3 | C33H37N3O13 | Yes&No |
beta-D-Glucose pentaacetate | 604-69-3 | C16H22O11 | Yes&No |
Gluconic acid | 526-95-4 | C6H12O7 | NO |
6-phosphogluconic acid | 921-62-0 | C6H13O10P | NO |
2,3,4,6-TETRA-O-ACETYL-BETA-D-GLUCOPYRANOSYL ISOTHIOCYANATE | 14152-97-7 | C15H19NO9S | Yes&No |
Galactose
Name | CAS | Formula | Acetate Groups Removed |
---|---|---|---|
Fmoc-L-Ser((Ac)3-β-D-GalNAc)-OH | 1676104-71-4 | C32H36N2O13 | Yes&No |
Fmoc-L-Ser((Ac)3-α-D-GalNAc)-OH | 120173-57-1 | C32H36N2O13 | Yes&No |
Fmoc-Thr(GalNAc(Ac)3-α-D)-OH | 116783-35-8 | C33H38N2O13 | Yes&No |
Fmoc-L-Thr(β-D-GalNAc(Ac)3)-OH | 133575-43-6 | C33H38N2O13 | Yes&No |
beta-D-Galactose pentaacetate | 4163-60-4 | C16H22O11 | Yes&No |
1,2,3,4,6-PENTA-O-ACETYL-ALPHA-D-GALACTOPYRANOSE | 4163-59-1 | C16H22O11 | Yes&No |
Mannose
Name | CAS | Formula | Acetate Groups Removed |
---|---|---|---|
Fmoc-L-Ser(ManNAc)-OH | Yes&No | ||
Fmoc-Thr(ManNAc)-OH | Yes&No | ||
α-D-MANNOSE ENTAACETATE | 4163-65-9 | C16H22O11 | Yes&No |
D-MANNOSE PENTAACETATE | 25941-03-1 | C16H22O11 | Yes&No |
D-Mannopyranose tetraacetate | 140147-37-1 | C14H20O10 | Yes&No |
References
Creative Peptides has accumulated a huge library of peptide knowledge including frontier peptide articles, application of peptides, useful tools, and more!
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